BDBM50394859 CHEMBL2165031

SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc(N)n2)N2CCN(C)CC2)cn1

InChI Key InChIKey=HJMSDMFCCDZFIX-UHFFFAOYSA-N

Data  4 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394859   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50394859(CHEMBL2165031)Copy SMILESCopy InChI

Affinity DataKi:  39nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kalpha expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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